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Programme

8th International Hypothermia and Temperature Management Symposium 2022
Registration form

Thursday June 16th 2022

Plenary session
Parallel sessions
Satellite symposia

9.00 – 9.30

Registration

Plenary session

Chairs: Janneke Horn and Marko Noc

9.30 – 9.40

Welcome

Luuk Otterspoor
Chair of the 8th International Hypothermia and Temperature Management Symposium
Catharina Hospital, Eindhoven, the Netherlands

9.40 – 10.00

Opening

John Jorritsma
Mayor of Eindhoven

10.00 – 10.30

Keynote lecture: Changes in practice of controlled hypothermia after cardiac arrest in the past 20 years – a critical care perspective

Hans Friberg
Professor at Anesthesiology and Intensive Care, Lund University, Sweden

10.30 – 10.55

Hypothermia: basic principles and clinical use

W. Dalton Dietrich
Professor, Neurological Surgery, Neurology, Biomedical Engineering and Cell Biology
Editor in chief, Therapeutic Hypothermia and Temperature Management
University of Miami Miller School of Medicine, Miami, USA

10.55 – 11.20

Hyperthermia: basic principles and clinical use

Hans Crezee
Principal Investigator for Hyperthermia Research, department of Radiation Oncology, Amsterdam
University Medical Centers University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands

11.20 – 11.40

The normal human temperature in 2022 and longevity

Julie Parsonnet
Professor in Infectious Diseases and Geographic Medicine
Stanford University Department of Medicine, Stanford, USA

11.40 – 12.00

Towards personalized TTM; Computational Prediction of Targeted Temperature Management

Robert Stevens
Director Division of Informatics, Integration, Innovation
Head Laboratory of Computational Intensive Care Medicine
Department of Anesthesiology and Critical Care Medicine, Neurology, and Radiology
Johns Hopkins University School of Medicine, Baltimore, USA

12.00 – 12.15

Panel discussion
All speakers and chairs

12.15 – 13.30

Lunch & E-poster presentations guided by key experts

5 e-posters will be guided and presented during this session. Moderators: Helen Bramlett and David Gaieski.

  1. Comparison of clinical risk scores in comatose patients admitted to intensive care after out-of-hospital cardiac arrest
  2. Hypothermia After Cardiac Arrest in Large Animals Trial (HACA-LA)
  3. The possibility to initiate cooling through cold air ventilation.
  4. Targeted Temperature Management after Intracerebral Hemorrhage (TTM-ICH): Results of a Prospective Randomized Clinical Trial
  5. Hybernia POST-Mechanical Thrombectomy Endovascular Cerebral Hypothermia trial in acute ischemic stroke (POST-MTECH trial)

Parallel session 1

Hypothermia and intensive care
  • Chairs: Hans Friberg and W. Dalton Dietrich
  • Room: Lichttoren

13.30 – 13.50

Current status and guidelines

Janneke Horn
Professor of Neuro-Intensive Care Medicine, Intensive Care / Amsterdam Neuroscience
Amsterdam UMC, Amsterdam, the Netherlands

13.50 – 14.10

Prognostication of patients in coma after cardiac arrest

Jeannette Hofmeijer
Professor at the Department of Clinical Neurophysiology
University of Twente, Enschede, the Netherlands

14.10 – 14.30

TTM, prognostication and new sedation techniques

Alexander Kersten
Senior Consultant for Cardiology and Critical Care
Heart Failure Specialist
Department of Cardiology, Vascular Medicine and Critical Care, Aachen, Germany

14.30 – 15.00

Tea break

15.00 – 15.20

ECMO and hypothermia

Dirk Donker
Professor of Cardiovascular and Respiratory Physiology University of Twente, Enschede, the Netherlands

15.20 – 15.40

Fever and delirium

Arjen Slooter
Professor of neuro-intensive care with focus of on Intensive Care of neurological- and neurosurgical patients, and on neurological complications of critical illness
University Medical Center, Utrecht, the Netherlands.

15.40 – 16.00

Phenotypes impacted by temperature and TTM in sepsis

Matt Harmon
AIOS Anesthesiology, LUMC

16.00 – 16.20

Towards personalized medicine. Which patients benefit the most from TTM on the ICU?

Jean-Baptiste Lascarrou
Intensivist, Medecine Intensive Reanimation, CHU Nantes, France

16.20 – 16.40

Panel discussion
All speakers and chairs

Parallel session 2

Temperature management in cardiac disease
  • Chairs: Patrick Lyden, Luuk Otterspoor
  • Room: Kelvin

13.30 – 13.55

Hypothermia to reduce myocardial infarct size: how did we get here?

Graham Nichol
Director
University of Washington-Harborview Center for Prehospital Emergency Care Washington, USA

13.55 – 14.20

Understanding the mechanisms of hypothermia in STEMI

Mohamed el Farissi
Cardiologist in training, PhD
Candidate on Selective Intracoronary Hypothermia
Catharina Hospital, Eindhoven, the Netherlands

14.20 – 14.45

Temperature management in cardiac electrophysiology

Lukas Dekker
Cardiologist, Catharina Hospital Eindhoven and Eindhoven University of Technology, The Netherlands

14.45 – 15.15

Tea break

15.15 – 15.40

Photonic and Conventional Temperature Measurements

Erik Korsten and Ton Backx

15.40 – 16.05

Therapeutic hypothermia, fundamental during cardiac and aortic surgery

Thomas van Brakel,
consultant Cardiothoracic surgeon, Catharina Hospital, Eindhoven, the Netherlands

16.05- 16.30

The future of hypothermia in cardiology

Marko Noc
Head of Centre for Intensive Internal Medicine
University Medical Centre, Ljubljana, Slovenia

16.30 – 16.45

Panel discussion
All speakers and chairs

17.00 – 18.00
Room: LED

Selective Intracoronary Hypothermia in STEMI Size: Practical Set-up and Performance (hands on workshop)

Nico Pijls en Mohamed el Farissi
Sponsored by Hexacath
Supported by Abbott

17.00 – 18.00
Room: Lichttoren

The ideal Targeted Temperature Management after cardiac arrest – what’s needed in clinical practice

David Gaieski, Graham Nichol and Andreas Schaefer
Sponsored by Zoll

17.00 – 18.00
Room: Elektron

TTM case presentations from the real world (trauma)

Janneke Horn and Matt Harmon
Sponsored by BD

17.00 – 18.00
Room: Kelvin

Future of intensive care: Inhaled sedation – A new sedation technique

Mattias Schindele, Alexander Kersten and Han Doreleijers
Sponsored by Sedana Medical

19.30 – 22.00

8th International Hypothermia and Temperature Management Symposium diner at the DAF museum

Address
Tongelresestraat 27
5613 DA Eindhoven
Tel. 040 – 24 44 364

Google Maps directions

Visit website

Friday June 17th 2022

Plenary session
Parallel sessions
Plenary closing session
Plenary session

Chairs: Julie Parsonnet en Robert Stevens

9.00 – 9.05

Opening

Janneke Horn
Professor of Neuro-Intensive Care Medicine, Intensive Care / Amsterdam Neuroscience
Amsterdam UMC, Amsterdam, the Netherlands

9.05 – 9.25

TTM2: where do we go from here?

Graham Nichol
Director
University of Washington-Harborview Center for Prehospital Emergency Care Washington, USA

9.25 – 9.50

Selective intracoronary hypothermia in STEMI; The EURO-ICE trial

Nico Pijls
Professor of Interventional Cardiology Heart Centre
Catharina Hospital, Eindhoven, the Netherlands

9.50 – 10.25

TTM in low-income and middle-income countries

Sudhin Thayyil
Professor of Perinatal Neuroscience and director of the Centre for Perinatal Neuroscience
Imperial College London, London, UK

10.25 – 11.00

Coffee break

11.00 – 11.25

Cold exposure and health

Matthijs Kox
Assistant Professor at the Department of Intensive Care Medicine of Radboud university medical centre, Nijmegen, the Netherlands

11.25 – 11.50

TTM for neurotrauma in adults and infants

Fabio Taccone
Professor at the Department of Intensive Care of Hopital Erasme and Professor of Emergency Medicine at the Université Libre de Bruxelles, Brussels, Belgium

11.50 – 12.15

What does the future hold for hypothermia in the ICU?

Stephen Bernard
Professor at Monash University
Department of Epidemiology and Preventive Medicine
The Alfred Hospital, Melbourne, Australia

12.15 – 13.30

Lunch & E-poster presentations guided by key experts

5 e-posters will be guided and presented during this session. Moderators: David Gaieski and Matthijs Kox.

  1. Non-invasive imaging combined with a 4-inflow preclinical hyperthermic intraperitoneal chemotherapy (HIPEC) setup ensuring a thermal stability and uniform drug delivery during HIPEC treatments in a peritoneal metastasis confirmed rat model
  2. Targeted Temperature Management for Severe Subarachnoid Hemorrhage Using Endovascular and Surface Cooling Systems: A Case-Control Study
  3. Effects of targeted temperature management at 33 C vs. 36 C on comatose patients after cardiac arrest stratified by the severity of encephalopathy
  4. Effect of hyperthermia and radiation therapy sequence on cell death and the immune phenotype of breast cancer cells
  5. COmbination of Targeted temperature management and Thrombectomy after acute Ischemic Stroke (COTTIS) – a pilot study

Parallel session 1

Temperature management in oncology
  • Chairs: Ignace de Hingh and Hans Crezee
  • Room: Lichttoren

13.30 – 13.50

Benefits of immunology and hyperthermia

Michael Rueckert
Scientist in Translational Radiobiology | Immunotherapy | Cancer Vaccines
Department of Radiation Oncology, Universitätsklinikum Erlangen

13.50 – 14.10

Status of and clinical trials of HIPEC

Ignace de Hingh
Surgeon at Catharina Cancer Institute Eindhoven
Professor at GROW University of Maastricht, the Netherlands

14.10 – 14.30

MRI for guiding and controlling thermal therapy

Maarten Paulides
Full Professor at Eindhoven University of Technology and Associate Professor at Erasmus MC Cancer Institute in Rotterdam

14.30 – 14.55

Tea break

14.55 – 15.15

Hyperthermia in the treatment of locally recurrent breast cancer

Geertjan van Tienhoven
Radiation oncologist at the Department of Radiation Oncology, Amsterdam University Medical Centers
University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands

15.15 – 15.35

Radiofrequency-induced thermochemotherapy for recurrent non–muscle-invasive Bladder Cancer

Fred Witjes
Oncological urologist, Radboud university medical centre, Nijmegen, the Netherlands

15.35 – 15.55

MR-HIFU Hyperthermia-mediated drug delivery

Lukas Sebeke
University Hospital of Cologne

15.55 – 16.10

Focused ultrasound-based hyperthermia for local drug delivery and immunotherapy applications with nanoparticles

Ashish Ranjan
Professor & Endowed Chair
Director: Institute for Translational and Emerging Research in Advanced Comparative Therapy (INTERACT)
College of Veterinary Medicine
Oklahoma State University

Parallel session 2

Temperature management in neurology
  • Chairs: Bart van Nuenen and Fred Rincon
  • Room: Kelvin

13.30 – 13.55

Hypothermia in ischemic stroke

Bart van der Worp
Professor of acute neurology with a special interest in cerebrovascular diseases at the University Medical Center, Utrecht, the Netherlands

13.55 – 14.20

Current status of hypothermia in neonatal hypoxic encephalopathy

Sudhin Thayyil
Professor of Perinatal Neuroscience and director of the Centre for Perinatal Neuroscience
Imperial College London, London, UK.

14.20-14.40

Tea break

14.40 – 15.05

TTM for status epilepticus

Alain Cariou
Professor of Therapeutics and Intensive Care at Paris Cité University, Paris, France

15.05 – 15.30

Impact of fever prevention in brain injured patients

Fabio Taccone
Professor at the Department of Intensive Care of Hopital Erasme and Professor of Emergency Medicine at the Université Libre de Bruxelles, Brussels, Belgium

Plenary closing session

Chairs: Marko Noc and Nico Pijls

16.15 – 16.30

Hyper- and hypothermia; what can they learn from each other?

Hans Crezee
Principal Investigator for Hyperthermia Research, department of Radiation Oncology, Amsterdam
University Medical Centers University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands

16.30 – 16.50

The future of temperature management

Patrick Lyden
Professor of Physiology and Neuroscience and Neurology, Department of Physiology and Neuroscience, University of Southern California, Los Angeles, USA

16.50 – 17.00

Wrap up and closing remarks

Luuk Otterspoor
Cardiologist and intensivist
Chair of the 8th International Hypothermia and Temperature Management Symposium
Catharina Hospital, Eindhoven, the Netherlands